Download Advances in Cancer Research, Vol. 28 by George Klein, Sidney Weinhouse (Eds.) PDF

By George Klein, Sidney Weinhouse (Eds.)

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Clin. Pathol. 21, 626-630. CANCER: SOMATIC-GENETIC CONSIDERATIONS 27 Baldwin, R. , and Barker, C. R. (1967). Br. J . Cancer 21, 338-345. Beard, J. (1902). Lancet 1, 1758-1761. Berenblum, I. (1941a). Cancer Res. 1, 4 4 4 8 . Berenblum, I. (1941b). Cancer Res. 1,807-814. , Newhouse, M. , and Turok, M. (1972). Lancet 2,476-479. , and di Mayorca, G. Nature (London)264,722-727. Brain, W. R. (Lord Brain), and Wilkinson, M. Brain 88, 465-478. Britten, R. , and Davidson, E. H. (1969). Science 165, 349-357.

Proc. Natl. Acad. Sci. A. 63, 428-435. Cleaver, J. , and Bootsma, D. Annu. Reu. Genet. 9, 19-38. Coggin, J. , and Anderson, N. G. Adu. Cancer Res. 19, 105-165. Cohnheim, J. (1889). ,London. Davidson, E. , and Britten, R. J. (1974). Cancer Res. 34,2034-2043. Davidson, E. , Hough, B. , Amenson, C. , and Britten, R. J. (1973)J. Mol. Biol. 77, 1-23. Day, R. S . (1975). Nature (London)253,748-749. Doll, R. Nature (London)265, 589-596. Drake, J. , and Baltz, R. H. Annu. Rev. Biochem. 45, 11-37. , and Preussmann, R.

The skin was involved in 179 patients, the skin and lips in another 20, and the lips only in 26. The various types of lesions are listed in Table V. Several features distinguish these skin cancers from those encountered in the general population. I n the public at large, basal cell carcinomas outnumber the squamous cell lesions (Bergstresser and Halprin, 1975), but in transplant recipients this relationship is reversed. , 1976). Multiple tumors are common and occurred in at least 87 of the 225 transplant recipients (39%), in contrast with an 44 ISRAEL PENN TABLE V NEOPLASMS OF THE SKIN AND LIPS Type of cancer Squamous cell carcinomas Basal cell carcinomas Squamous and basal cell carcinomas Malignant melanoma Unclassified Number of patients 127 59 25 10" 4 225 a One patient also had a squamous cell carcinoma, and another had multiple basal cell carcinomas.

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