Download Cytokines as Potential Therapeutic Targets for Inflammatory by R. Numerof, Charles A. Dinarello, Khusru Asadullah PDF

By R. Numerof, Charles A. Dinarello, Khusru Asadullah

Cytokines and cytokine receptors stay a space of significant curiosity for the improvement of particular treatments for cutaneous inflammatory illnesses. Anti-TNF therapeutics have confirmed to be powerful within the therapy of psoriasis, and medical investigations have now started for different cytokine-directed treatments, akin to these concentrating on IFN-g, IL-12p40, and IL-18. as well as therapeutics that focus on cytokines without delay, thoughts that focus on cytokine signaling pathways are in improvement. This e-book summarizes the findings of the 56th foreign Workshop of the Ernst Schering examine beginning that eager about "Cytokines as capability healing goals for Inflammatory pores and skin Diseases".

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Clin Immunol Immunopathol 88:232–240 Giri JG, Kumaki S, Ahdieh M, Friend DJ, Loomis A, Shanebeck K, DuBose R, Cosman D, Park LS, Anderson DM (1995) Identification and cloning of a novel IL-15 binding protein that is structurally related to the alpha chain of the IL-2 receptor. EMBO J 14:3654–3663 Gonzalez-Alvaro I, Ortiz AM, Garcia-Vicuna R, Balsa A, Pascual-Salcedo D, Laffon A (2003) Increased serum levels of interleukin-15 in rheumatoid arthritis with long- term disease. Clin Exp Rheumatol 21:639–642 Grabstein KH, Eisenman J, Shanebeck K, Rauch C, Srinivasan S, Fung V, Beers C, Richardson J, Schoenborn MA, Ahdieh M, Johnson L, Alderson MR, Watson JD, Anderson DM, Giri JG (1994) Cloning of a T cell growth factor that interacts with the beta chain of the interleukin-2 receptor.

2002). Certain endogenous and exogenous factors (genetic, viruses, bacteria, fungi, in some cases sex hormones, parasites, and others) may be involved in the initiation of autoimmune diseases and may induce IFN-γ. Scientists have implicated Epstein-Barr virus, mycobacteria, Proteus, and Escheria coli, for example, in the pathogenesis of rheumatoid arthritis (Harrison and McColl 1998). Human endogenous retroviruses (HERV) have been found in patients with multiple sclerosis (Christensen et al. 2001) and schizophrenia (Karlsson et al.

Basic and clinical aspects. John Wiley & Sons, New York, p. 325 Snider LA and Swedo SE (2003) Post-streptococcal autoimmune disorders of the central nervous system. Curr Opin Neurol 16:359–365 Tang H, Mignon-Godefroy K, Meroni PL, Garotta G, Charreire J, Nicoletti F (1993) The effects of a monoclonal antibody to interferon-gamma on experimental autoimmune thyroiditis (EAT): prevention of disease and decrease of EAT-specific T cells. Eur J Immunol 23:275–278 Tang L, Cao L, Bernardo O, Chen Y, Sundberg JP, Lui H, Chung S, Shapiro J (2003) Topical mechlorethamine restores autoimmune-arrested follicular activity in mice with an alopecia areata-like disease by targeting infiltrated lymphocytes.

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